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class=\"swell-block-accordion\">\n<details class=\"swell-block-accordion__item\" data-swl-acc=\"wrapper\"><summary class=\"swell-block-accordion__title\" data-swl-acc=\"header\"><span class=\"swell-block-accordion__label\">\u3010\u53c2\u8003\u6587\u732e\u3011<\/span><span class=\"swell-block-accordion__icon c-switchIconBtn\" data-swl-acc=\"icon\" aria-hidden=\"true\" data-opened=\"false\"><i class=\"__icon--closed icon-caret-down\"><\/i><i class=\"__icon--opened icon-caret-up\"><\/i><\/span><\/summary><div class=\"swell-block-accordion__body\" data-swl-acc=\"body\">\n<p>Jastreboff AM, et al. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med. 2022;387(3):205-216.<br>DOI: 10.1056\/NEJMoa2206038<br>Wadden TA, et al. Tirzepatide after intensive lifestyle intervention in adults with overweight or obesity: the SURMOUNT-3 phase 3 trial. Nature Medicine. 2024.<br>DOI: 10.1038\/s41591-023-02597-w<br>Aronne LJ, et al. Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: The SURMOUNT-4 Randomized Clinical Trial. JAMA. 2024;331(1):38-48.<br>DOI: 10.1001\/jama.2023.24945<br>Aronne LJ, et al. Tirzepatide as Compared with Semaglutide for the Treatment of Obesity. N Engl J Med. 2025;393(1).<br>DOI: 10.1056\/NEJMoa2416394<\/p>\n\n\n\n<p><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11576767\/\">Efficacy and safety of tirzepatide versus placebo in overweight or obese adults without diabetes: a systematic review and meta-analysis of randomized controlled trials. PMC. 2024.<\/a><br>Tirzepatide for overweight and obesity management. Expert Opinion on Pharmacotherapy. 2024.<br>DOI: 10.1080\/14656566.2024.2436595<br><br><a href=\"https:\/\/pins.japic.or.jp\/pdf\/newPINS\/00070640.pdf\">\u30de\u30f3\u30b8\u30e3\u30ed \u96fb\u5b50\u5316\u3055\u308c\u305f\u6dfb\u4ed8\u6587\u66f8<\/a>\uff08\u65e5\u672c\u30a4\u30fc\u30e9\u30a4\u30ea\u30ea\u30fc\u682a\u5f0f\u4f1a\u793e\u3001\u6700\u7d42\u6539\u8a022025\u5e7412\u6708\uff09<br><a href=\"https:\/\/pins.japic.or.jp\/pdf\/medical_interview\/IF00007732.pdf\">\u30a4\u30f3\u30bf\u30d3\u30e5\u30fc\u30d5\u30a9\u30fc\u30e0<\/a>\uff08\u65e5\u672c\u75c5\u9662\u85ac\u5264\u5e2b\u4f1a\u8a18\u8f09\u8981\u9818\u6e96\u62e0\u30012025\u5e7412\u6708\u6539\u8a02\u7b2c9\u7248\uff09<br><a href=\"https:\/\/www.pmda.go.jp\/drugs\/2022\/P20221014001\/530471000_30400AMX00420_A100_1.pdf\">PMDA \u5be9\u8b70\u7d50\u679c\u5831\u544a\u66f8<\/a>\uff08\u4ee4\u548c4\u5e748\u670829\u65e5\uff09<br><a href=\"https:\/\/www.mhlw.go.jp\/content\/10808000\/001440799.pdf\">\u6700\u9069\u4f7f\u7528\u63a8\u9032\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3 \u30c1\u30eb\u30bc\u30d1\u30c1\u30c9\uff08\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\uff09\uff08\u539a\u751f\u52b4\u50cd\u7701\uff09<\/a><br><br>Samms RJ, Coghlan MP, Sloop KW. How may GIP enhance the therapeutic efficacy of GLP-1? Trends Endocrinol Metab. 2020;31(6):410-421.<br>Hammoud R, Drucker DJ. Beyond the pancreas: contrasting cardiometabolic actions of GIP and GLP1. Nat Rev Endocrinol. 2023;19:201-216.<\/p>\n<\/div><\/details>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u3088\u304f\u3042\u308b\u8cea\u554f\uff08FAQ\uff09<\/h2>\n\n\n\n<dl class=\"swell-block-faq -icon-rounded is-style-faq-stripe\" data-q=\"col-custom\" data-a=\"col-custom\">\n<div class=\"swell-block-faq__item\"><dt class=\"faq_q\">\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3069\u306e\u304f\u3089\u3044\u306e\u671f\u9593\u3067\u52b9\u679c\u3092\u611f\u3058\u3084\u3059\u3044\u3067\u3059\u304b\uff1f<\/dt><dd 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